1,2-pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester
1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester
CAS: 144829-96-9
Molecular Formula: C20H19NO4
1,2-pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester - Names and Identifiers
1,2-pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester - Physico-chemical Properties
| Molecular Formula | C20H19NO4 |
| Molar Mass | 337.37 |
1,2-pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester - Introduction
1, + acid, 1-(9H-fluoren-9-ylmethyl) ester is an amino acid protecting group commonly used in peptide synthesis and biochemical studies. Its properties are as follows: the chemical name is (9H-Fluoren-9-yl)methoxycarbonyl-DL-proline, the chemical formula is C23H19NO4, and the molecular weight is 373.40g/mol.
1, acid, 1-(9H-fluoren-9-ylmethyl) ester is one of the main uses as an amino acid protecting group in peptide synthesis. It can be deprotected by a dense non-conducting layer (DMF) or dimethyl sulfide (DMS), allowing proline to participate in the elongation and assembly of the peptide chain.
1, acid, 1-(9H-fluoren-9-ylmethyl) ester is generally prepared by reacting proline with (9h-fluoren-9-yl) Methanol ester (Fmoc-Cl). Fmoc-Cl is first reacted with a base (such as pyrrolidine) to produce Fmoc (Fmoc-OH), and then proline Fmoc-OH is reacted with acid acid, 1-(9H-fluoren-9-ylmethyl) ester.
pay attention to some safety information when using 1, acid, 1-(9H-fluoren-9-ylmethyl) ester. It is organic, so contact with strong oxidants and strong acids should be avoided to prevent danger. During operation, appropriate protective measures should be taken, such as gloves, goggles and protective clothing. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
During storage, 1, acid, 1-(9H-fluoren-9-ylmethyl) ester should be stored in a dry, sealed container away from direct sunlight. Proper storage extends its expiration date and ensures the accuracy and reliability of subsequent experiments.
to sum up, 1, acid, 1-(9H-fluoren-9-ylmethyl) ester is a commonly used amino acid protecting group, which is widely used in peptide synthesis and biochemical research. In the use and storage should pay attention to safety, and in accordance with the correct method of synthesis.
1, acid, 1-(9H-fluoren-9-ylmethyl) ester is one of the main uses as an amino acid protecting group in peptide synthesis. It can be deprotected by a dense non-conducting layer (DMF) or dimethyl sulfide (DMS), allowing proline to participate in the elongation and assembly of the peptide chain.
1, acid, 1-(9H-fluoren-9-ylmethyl) ester is generally prepared by reacting proline with (9h-fluoren-9-yl) Methanol ester (Fmoc-Cl). Fmoc-Cl is first reacted with a base (such as pyrrolidine) to produce Fmoc (Fmoc-OH), and then proline Fmoc-OH is reacted with acid acid, 1-(9H-fluoren-9-ylmethyl) ester.
pay attention to some safety information when using 1, acid, 1-(9H-fluoren-9-ylmethyl) ester. It is organic, so contact with strong oxidants and strong acids should be avoided to prevent danger. During operation, appropriate protective measures should be taken, such as gloves, goggles and protective clothing. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
During storage, 1, acid, 1-(9H-fluoren-9-ylmethyl) ester should be stored in a dry, sealed container away from direct sunlight. Proper storage extends its expiration date and ensures the accuracy and reliability of subsequent experiments.
to sum up, 1, acid, 1-(9H-fluoren-9-ylmethyl) ester is a commonly used amino acid protecting group, which is widely used in peptide synthesis and biochemical research. In the use and storage should pay attention to safety, and in accordance with the correct method of synthesis.
Last Update：2024-04-10 22:29:15
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